Stevens-Johnson Syndrome Associated to the Administration of Janssen AD26.COV2.S COVID-19 Vaccine in Tijuana, Baja California, México, a Case Report
Daniel Pacheco Ambriz,
Lorena Lizbeth Félix Guerrero,
Giselle Anahí Olivas Cárdenas,
Alicia Pastora Amarillas Villalvazo,
Lorena Diaz Amezquita
Issue:
Volume 8, Issue 1, June 2022
Pages:
1-4
Received:
10 November 2021
Accepted:
7 December 2021
Published:
24 January 2022
DOI:
10.11648/j.ijcoms.20220801.11
Downloads:
Views:
Abstract: Background: Stevens-Johnson syndrome and toxic epidermal necrolysis are rare pathologies characterized by mucocutaneous involvement, considered as late hypersensitivity mainly associated with drugs. Other less frequent causes include infections, vaccines, systemic diseases and botanical medicine. COVID-19 vaccines can cause adverse reactions mainly from vaccine- induced immune responses. We present a clinical case of a patient with Stevens-Johnson syndrome diagnose, without no history of factors related to this pathology, except for the use of Ad26.COV2.S (Janssen/Johnson & Johnson) vaccine Clinical case: A 20 years old male patient with clinical and histopathological characteristics compatible with Stevens Johnson syndrome and whose background history was the application of the Ad26.COV2.S vaccine (Janssen / Johnson & Johnson) 11 days prior to the start of the disease. At arrival at the emergency room he got a dermatologic consult who started treatment with metilprednisolone 1gr intravenously, Aciclovir 200mg orally and topic fluocinolone. He was hospitalized in charge of dermatology presenting improvement deciding outpatient treatment. Five days after his hospital discharge, at dermatology external consultation he´s found with overall improvement and fewer dermic lesions. Conclusions: At this time we didn’t find a case where they reported Stevens-Johnson syndrome associated to Ad26.COV2.S vaccine. Although the information regarding the adverse effects of the new vaccines against COVID-19 is still limited, there is the possibility of a direct association between the Ad26.COV2.S vaccine and a Stevens Johnson Syndrome.
Abstract: Background: Stevens-Johnson syndrome and toxic epidermal necrolysis are rare pathologies characterized by mucocutaneous involvement, considered as late hypersensitivity mainly associated with drugs. Other less frequent causes include infections, vaccines, systemic diseases and botanical medicine. COVID-19 vaccines can cause adverse reactions mainly...
Show More
Unusual Oral Squamous Papilloma Imitating Exophytic Carcinoma: A Case Presentation
Abbas Alramzi,
Maysoun Kassem,
Ashraf Barghash,
Sara Khraibut
Issue:
Volume 8, Issue 1, June 2022
Pages:
5-7
Received:
6 April 2022
Accepted:
4 May 2022
Published:
24 May 2022
DOI:
10.11648/j.ijcoms.20220801.12
Downloads:
Views:
Abstract: Background: Oral squamous papilloma (OSP) specifies a generally benign slowly growing usually painless epithelial pathologic overgrowth. Although the exact etiology of OSP is debatable, human papilloma virus (HPV) is suggested to be an etiologic factor. Human papilloma viruses (HPVs) are associated with various benign and malignant lesions of mucosa and skin and may present as a proliferation of the stratified squamous epithelium which classically results in papillary exophytic growths. Current epidemiologic studies show that HPVs can be an essential carcinogen for the development of oral and oropharyngeal cancer. OSP is visible to the naked eye, and approached by conventional visual and tactile examination (CVTE). Currently the preferred treatment modality for the management of such persistent growth is surgical excision, which also secures a definitive diagnosis through histopathological evaluation. Objective: This article aims to present a case of a labial sessile overgrowth that mimics exophytic carcinoma and to describe its management. Based on histopathological analysis the diagnosis was confirmed as OSP. Method: We describe the management of a lower labial lesion that doubts -at first glance- presence of malignancy. Result: After surgical excision of the lesion, patient restored satisfactorily both function and esthetic of lower lip, with no recurrence. Conclusion: Authors emphasize that correct clinical judgement in addition to incisional biopsy are all of paramount importance in initial management of oral suspicious lesions.
Abstract: Background: Oral squamous papilloma (OSP) specifies a generally benign slowly growing usually painless epithelial pathologic overgrowth. Although the exact etiology of OSP is debatable, human papilloma virus (HPV) is suggested to be an etiologic factor. Human papilloma viruses (HPVs) are associated with various benign and malignant lesions of mucos...
Show More
Risks and Complications in Patients with Oral Cancer
Issue:
Volume 8, Issue 1, June 2022
Pages:
8-15
Received:
12 May 2022
Accepted:
27 May 2022
Published:
31 May 2022
DOI:
10.11648/j.ijcoms.20220801.13
Downloads:
Views:
Abstract: Oral cancer is a multifactorial disease of unknown origin, which affects millions of people in the world. Its attention and treatment must be carried out in multidisciplinary teams, since it becomes complex for the dental professional to carry out its management independently. This motivated the realization of the present investigation with the objective of describing the main risks and complications in patients with oral cancer. To do this, an exhaustive bibliographic review was carried out based on national and international literature, using different descriptors in English and Spanish. The previous experience of the author was taken into account. Then a critical analysis was carried out, where the main risks and complications that can occur in these patients were compiled. Dissimilar conditions and the scope of the therapeutic procedures carried out in these patients with oral cancer were illustrated. The content was organized by anatomical regions and surgical treatments. It exposes in a structured and schematic way several of the complications that can occur in these procedures. At the end of the investigation, it is concluded that there are multiple complications and risks to which these patients are exposed, causing functional, mechanical, aesthetic, psychological and nutritional alterations.
Abstract: Oral cancer is a multifactorial disease of unknown origin, which affects millions of people in the world. Its attention and treatment must be carried out in multidisciplinary teams, since it becomes complex for the dental professional to carry out its management independently. This motivated the realization of the present investigation with the obj...
Show More
